Disposition of fullerene C60 in rats following intratracheal or intravenous administration

Created on 2022-09-03T10:21:23-05:00

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1mg/kg body weight and 5mg/kg was tested on rats.

C60 accumulated in the liver, spleen, lung and kidneys.

C60 filtered out of the kidneys fastest (24 hour half life) followed by lungs (139 hour half life) while the liver only lost 10% by the end of 168 hour test period.