Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture
Created on 2021-08-09T00:36:56-05:00
We tested the effects of milk thistle (Silybum marianum) extract on the differentiation and survival of cultured neural cells. Milk thistle enhanced nerve growth factor (NGF)-induced neurite outgrowth in PC-12 neural cells and prolonged their survival in culture. Milk thistle extract also protected cultured rat hippocampal neurons against oxidative stress-induced cell death.